二甲基乙烯雌酚

化合物

二甲基乙烯雌酚(英語:Dimethylstilbestrol,缩写DMS,也称为丁烯雌酚)是一种有机化合物,化学式C16H16O2,属于芪类非甾体雌激素,相比己烯雌酚少二个甲基,从未上市销售。[1][2][3][4][5]:213

二甲基乙烯雌酚
臨床資料
其他名稱DMS; (Ε)-α,α'-Dimethyl-4,4'-stilbenediol
藥物類別英语Drug class非甾体雌激素
识别信息
  • 4-[(E)-3-(4-hydroxyphenyl)but-2-en-2-yl]phenol
CAS号552-80-7
13366-36-4)
PubChem CID
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
化学信息
化学式C16H16O2
摩尔质量240.30 g·mol−1
3D模型(JSmol英语JSmol
  • C/C(=C(/C)\C1=CC=C(C=C1)O)/C2=CC=C(C=C2)O
  • InChI=1S/C16H16O2/c1-11(13-3-7-15(17)8-4-13)12(2)14-5-9-16(18)10-6-14/h3-10,17-18H,1-2H3/b12-11+
  • Key:XPINIPXARSNZDM-VAWYXSNFSA-N

参考文献

  1. ^ Pincus G. Blastocyst Development and Implantation. The Control of Fertility. Elsevier. 3 September 2013: 126–. ISBN 978-1-4832-7088-3. 
  2. ^ Emmens CW, Martin L. Anti-Estrogens. Dorfman RI (编). Steroidal Activity in Experimental Animals and Man. Elsevier Science. 5 December 2016: 83–. ISBN 978-1-4832-7299-3. 
  3. ^ Hilf R, Wittliff JL. Mechanisms of Action of Estrogens. Sartorelli AC, Johns DG (编). Antineoplastic and Immunosuppressive Agents. Springer Science & Business Media. 27 November 2013: 110–. ISBN 978-3-642-65806-8. 
  4. ^ Horwitz KB, McGuire WL. Antiestrogens: Mechanism of Action and Effects in Breast Cancer. McGuire W (编). Experimental Biology. Springer Science & Business Media. 14 December 2013: 169–. ISBN 978-1-4757-4673-0. 
  5. ^ Knörr K, Beller FK, Lauritzen C. Prinzipien der Hormonbehandlung: Die wichtigsten hormonalen Behandlungsmethoden. Lehrbuch der Gynäkologie. Springer-Verlag. 17 April 2013. ISBN 978-3-662-00942-0. 

外部链接