二甲炔酮

二甲炔酮,也译作地美炔酮(英語:Dimethisterone商品名:Lutagan 或 Secrosteron等)是一种黄体制剂药物,过去被用于治疗一些妇科疾病以及作为避孕药,但现在已不再使用[1][2][3][4]

二甲炔酮
Skeletal formula of dimethisterone
Ball-and-stick model of the dimethisterone molecule
臨床資料
商品名英语Drug nomenclatureLutagan, Secrosteron, others
其他名稱Dimethindrone; 6α,21-Dimethylethisterone; 6α,21-Dimethyl-17α-ethynyltestosterone; 17α-Ethynyl-6α,21-dimethylandrost-4-en-17β-ol-3-one; 6α,21-Dimethyl-17β-hydroxy-17α-pregn-4-en-20-yn-3-one
给药途径口服给药
藥物類別英语Drug classProgestin; Progestogen
识别信息
  • (6S,8R,9S,10R,13S,14S,17S)-17-hydroxy-6,10,13-trimethyl-17-prop-1-ynyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
CAS号79-64-1
PubChem CID
ChemSpider
UNII
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
ECHA InfoCard100.001.106 編輯維基數據鏈接
化学信息
化学式C23H32O2
摩尔质量340.51 g·mol−1
3D模型(JSmol英语JSmol
  • CC#C[C@@]1(CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2C[C@@H](C4=CC(=O)CC[C@]34C)C)C)O
  • InChI=1S/C23H32O2/c1-5-9-23(25)12-8-19-17-13-15(2)20-14-16(24)6-10-21(20,3)18(17)7-11-22(19,23)4/h14-15,17-19,25H,6-8,10-13H2,1-4H3/t15-,17+,18-,19-,21+,22-,23-/m0/s1
  • Key:LVHOURKCKUYIGK-RGUJTQARSA-N

参考文献

  1. ^ J. Elks. The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. 14 November 2014: 430– [2019-06-25]. ISBN 978-1-4757-2085-3. (原始内容存档于2020-08-03). 
  2. ^ Rodolfo Paoletti; N. Pasetto; J.L. Ambrus. The Menopause and Postmenopause: The Proceedings of an International Symposium held in Rome, June 1979. Springer Science & Business Media. 6 December 2012: 374–. ISBN 978-94-011-7230-1. 
  3. ^ Earl A. Surwit; David Alberts. Endometrial Cancer. Springer Science & Business Media. 6 December 2012: 11– [2019-06-25]. ISBN 978-1-4613-0867-6. (原始内容存档于2020-08-01). 
  4. ^ Richard Patterson. Drugs in Litigation: Damage Awards Involving Prescription and Nonprescription Drugs. LexisNexis. 21 December 2012: 483–484. ISBN 978-0-327-18698-4.