冠狗牙花定碱

冠狗牙花定碱
臨床資料
ATC碼	未分配;
识别信息
	IUPAC命名法 Methyl (1S,15R,17S,18S)-17-ethyl-3,13-diazapentacyclo[13.3.1.02,10.04,9.013,18]nonadeca-2(10),4,6,8-tetraene-1-carboxylate; ;
CAS号	467-77-6
PubChem CID	6426909;
ChemSpider	4932328;
ChEBI	CHEBI:3887;
CompTox Dashboard（英语：CompTox Chemicals Dashboard） (EPA)	DTXSID60963642 ;
ECHA InfoCard	100.006.727
化学信息
化学式	C21H26N2O2
摩尔质量	338.45 g·mol−1
3D模型（JSmol（英语：JSmol））	交互式图像;
	SMILES CCC1CC2CC3(C1N(C2)CCC4=C3NC5=CC=CC=C45)C(=O)OC;
	InChI InChI=1S/C21H26N2O2/c1-3-14-10-13-11-21(20(24)25-2)18-16(8-9-23(12-13)19(14)21)15-6-4-5-7-17(15)22-18/h4-7,13-14,19,22H,3,8-12H2,1-2H3/t13-,14+,19+,21-/m1/s1; Key:NVVDQMVGALBDGE-PZXGUROGSA-N;

冠狗牙花定碱（英語：Coronaridine，简称狗牙花定碱、狗牙花定、狗牙花碱，也称为18-甲氧羰基伊波加明，18-carbomethoxyibogamine）是一种有机化合物，化学式为C₂₁H₂₆N₂O₂，是山马茶（学名：Tabernaemontana divaricata）等马蹄花属植物中提取的生物碱^[1]。

参考文献

^ Delorenzi JC, Freire-de-Lima L, Gattass CR, de Andrade Costa D, He L, Kuehne ME, Saraiva EM. In vitro activities of iboga alkaloid congeners coronaridine and 18-methoxycoronaridine against Leishmania amazonensis. Antimicrobial Agents and Chemotherapy. July 2002, 46 (7): 2111–2115. PMC 127312  . PMID 12069962. doi:10.1128/aac.46.7.2111-2115.2002.

[pmid12069962-1] Delorenzi JC, Freire-de-Lima L, Gattass CR, de Andrade Costa D, He L, Kuehne ME, Saraiva EM. In vitro activities of iboga alkaloid congeners coronaridine and 18-methoxycoronaridine against Leishmania amazonensis. Antimicrobial Agents and Chemotherapy. July 2002, 46 (7): 2111–2115. PMC 127312  . PMID 12069962. doi:10.1128/aac.46.7.2111-2115.2002.

[1]

臨床資料


ATC碼	未分配
识别信息
IUPAC命名法 Methyl (1S,15R,17S,18S)-17-ethyl-3,13-diazapentacyclo[13.3.1.0^2,10.0^4,9.0^13,18]nonadeca-2(10),4,6,8-tetraene-1-carboxylate
CAS号	467-77-6
PubChem CID	6426909
ChemSpider	4932328
ChEBI	CHEBI:3887
CompTox Dashboard（英语：CompTox Chemicals Dashboard） (EPA)	DTXSID60963642
ECHA InfoCard	100.006.727
化学信息
化学式	C₂₁H₂₆N₂O₂
摩尔质量	338.45 g·mol⁻¹
3D模型（JSmol（英语：JSmol））	交互式图像
SMILES CCC1CC2CC3(C1N(C2)CCC4=C3NC5=CC=CC=C45)C(=O)OC
InChI InChI=1S/C21H26N2O2/c1-3-14-10-13-11-21(20(24)25-2)18-16(8-9-23(12-13)19(14)21)15-6-4-5-7-17(15)22-18/h4-7,13-14,19,22H,3,8-12H2,1-2H3/t13-,14+,19+,21-/m1/s1 Key:NVVDQMVGALBDGE-PZXGUROGSA-N