异烟酸
异烟酸(吡啶-4-甲酸)是一种有机化合物,化学式为C5H4N(CO2H),是吡啶甲酸的同分异构体之一。它可由吡啶-4-甲醛[1]、吡啶-4-甲醇[2]或4-甲基吡啶[3]的氧化反应制得。它和氯化亚砜反应,可以得到吡啶-4-甲酰氯。[4]
异烟酸 | |||
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IUPAC名 Pyridine-4-carboxylic acid | |||
别名 | 4-吡啶甲酸 吡啶-4-甲酸 | ||
识别 | |||
CAS号 | 55-22-1 ![]() | ||
PubChem | 5922 | ||
ChemSpider | 5709 | ||
SMILES |
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InChI |
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InChIKey | TWBYWOBDOCUKOW-UHFFFAOYAV | ||
ChEBI | 6032 | ||
KEGG | C07446 | ||
性质 | |||
化学式 | C6H5NO2 | ||
摩尔质量 | 123.11 g·mol−1 | ||
外观 | 白色晶体 | ||
熔点 | 310 °C(583 K)(升华) | ||
危险性 | |||
NFPA 704 | |||
相关物质 | |||
相关化学品 | 异烟肼 | ||
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。 |
参考文献
- ^ Robert H. Dodd, Mireille Le Hyaric. The Oxidation of Aromatic Aldehydes to Carboxylic Acids Using Hydrogen Peroxide in Formic Acid. Synthesis. 1993, 1993 (03): 295–297 [2020-09-20]. ISSN 0039-7881. doi:10.1055/s-1993-25851. (原始内容存档于2018-06-05) (英语).
- ^ Susanta Hazra, Mayukh Deb, Anil J. Elias. Iodine catalyzed oxidation of alcohols and aldehydes to carboxylic acids in water: a metal-free route to the synthesis of furandicarboxylic acid and terephthalic acid. Green Chemistry. 2017, 19 (23): 5548–5552 [2020-09-20]. ISSN 1463-9262. doi:10.1039/C7GC02802D (英语).
- ^ Parker, Kathlyn A.; Ledeboer, Mark W.; Pettigrew, Jeremy D. Nitric acid. e-EROS Encyclopedia of Reagents for Organic Synthesis, 2009. pp 1-7. ISBN 978-0-470-84289-8.
- ^ Kang-Min Wang, Yuan-Cheng Qin, Guan-Jun Cheng, Hua-Jun Zhu, Long Liang, Zhi-Peng Cheng, Mei-Ming Luo. Design, Synthesis and Antibacterial Evaluation of Novel Fluoroquinolone and its Derivatives. Asian Journal of Chemistry. 2014, 26 (1): 209–215 [2020-09-20]. doi:10.14233/ajchem.2014.15572. (原始内容存档于2022-02-25).