毒嘧啶

化合物

毒嘧啶(英語:Toxopyrimidine,也称4-氨基-5-羟基甲基-2-甲基嘧啶4-Amino-5-Hydroxymethyl-2-Methylpyrimidine)是一种含氮杂环有机化合物,化学式为C6H9N3O,能作为维生素B6拮抗剂[2][3]

毒嘧啶
IUPAC名
(4-Amino-2-methylpyrimidin-5-yl)methanol
别名 Pyramin[1]
识别
CAS号 73-67-6
PubChem 777
ChemSpider 756
SMILES
 
  • Cc1ncc(c(n1)N)CO
InChI
 
  • 1S/C6H9N3O/c1-4-8-2-5(3-10)6(7)9-4/h2,10H,3H2,1H3,(H2,7,8,9)
InChIKey VUTBELPREDJDDH-UHFFFAOYSA-N
性质
化学式 C6H9N3O
摩尔质量 139.16 g·mol−1
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。

参考文献

  1. ^ Haughton BG, King HK. Toxo-pyrimidine phosphate as an inhibitor of bacterial enzyme systems that require pyridoxal phosphate. The Biochemical Journal. December 1958, 70 (4): 660–5. PMC 1196724 . PMID 13607425. doi:10.1042/bj0700660. 
  2. ^ Rindi G, Ferrari G. The gamma-aminobutyric acid and glutamic acid content of brains of rats treated with toxopyrimidine. Nature. February 1959, 183 (4661): 608–9. Bibcode:1959Natur.183..608R. PMID 13632808. S2CID 4200644. doi:10.1038/183608a0. 
  3. ^ Rindi G, Perri V, Ventura U. Effect of toxopyrimidine on glutamic-decarboxylase and glutamic-oxalacetic transaminase of rat brain. Nature. April 1959, 183 (4668): 1126–7. Bibcode:1959Natur.183.1126R. PMID 13657025. S2CID 4209134. doi:10.1038/1831126a0. 

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