毒嘧啶
化合物
毒嘧啶(英語:Toxopyrimidine,也称4-氨基-5-羟基甲基-2-甲基嘧啶,4-Amino-5-Hydroxymethyl-2-Methylpyrimidine)是一种含氮杂环有机化合物,化学式为C6H9N3O,能作为维生素B6的拮抗剂[2][3]。
毒嘧啶 | |
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IUPAC名 (4-Amino-2-methylpyrimidin-5-yl)methanol | |
别名 | Pyramin[1] |
识别 | |
CAS号 | 73-67-6 |
PubChem | 777 |
ChemSpider | 756 |
SMILES |
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InChI |
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InChIKey | VUTBELPREDJDDH-UHFFFAOYSA-N |
性质 | |
化学式 | C6H9N3O |
摩尔质量 | 139.16 g·mol−1 |
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。 |
参考文献
- ^ Haughton BG, King HK. Toxo-pyrimidine phosphate as an inhibitor of bacterial enzyme systems that require pyridoxal phosphate. The Biochemical Journal. December 1958, 70 (4): 660–5. PMC 1196724 . PMID 13607425. doi:10.1042/bj0700660.
- ^ Rindi G, Ferrari G. The gamma-aminobutyric acid and glutamic acid content of brains of rats treated with toxopyrimidine. Nature. February 1959, 183 (4661): 608–9. Bibcode:1959Natur.183..608R. PMID 13632808. S2CID 4200644. doi:10.1038/183608a0.
- ^ Rindi G, Perri V, Ventura U. Effect of toxopyrimidine on glutamic-decarboxylase and glutamic-oxalacetic transaminase of rat brain. Nature. April 1959, 183 (4668): 1126–7. Bibcode:1959Natur.183.1126R. PMID 13657025. S2CID 4209134. doi:10.1038/1831126a0.