猪胆酸

猪胆酸
别名	γ-Muricholic acid; Iocholic acid; 3α,6α,7α-Trihydroxy-5β-cholan-24-oic acid
识别
CAS号	547-75-1
PubChem	92805
SMILES	C[C@H](CCC(=O)O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2[C@@H]([C@@H]([C@H]4[C@@]3(CC[C@H](C4)O)C)O)O)C;
ChEBI	81244
KEGG	C17649
性质
化学式	C24H40O5
摩尔质量	408.57 g·mol−1
	若非注明，所有数据均出自标准状态（25 ℃，100 kPa）下。

猪胆酸（英語：Hyocholic acid，也被称为3α,6α,7α-三羟基-5β-胆烷-24-羧酸，3α,6α,7α-trihydroxy-5β-cholan-24-oic acid）是猪胆汁酸的主要成分^[1]，在人类胆汁酸中有很低的浓度^[2]^[3]。猪胆酸和人类胆汁酸的主要成分之一胆酸的不同在于第三个羟基基团位于6-号碳原子的α-位而不是12α位。人类胆汁酸的另一种主要成分鹅去氧胆酸则既没有6-号位也没有12-号位的羟基基团。另外，猪胆酸也和大鼠的鼠胆酸不同，α和β鼠胆酸的6号位都为6β-羟基。

参考文献

^ Haslewood, GA. Bile salts of germ-free domestic fowl and pigs.. The Biochemical Journal. June 1971, 123 (1): 15–8. PMC 1176895  . PMID 5128663. doi:10.1042/bj1230015.
^ Bathena, SP; Mukherjee, S; Olivera, M; Alnouti, Y. The profile of bile acids and their sulfate metabolites in human urine and serum.. Journal of Chromatography B. 30 December 2013,. 942-943: 53–62. PMID 24212143. doi:10.1016/j.jchromb.2013.10.019.
^ Russell DW. The enzymes, regulation, and genetics of bile acid synthesis. Annu. Rev. Biochem. 2003, 72: 137–74. PMID 12543708. doi:10.1146/annurev.biochem.72.121801.161712.

[1] Haslewood, GA. Bile salts of germ-free domestic fowl and pigs.. The Biochemical Journal. June 1971, 123 (1): 15–8. PMC 1176895  . PMID 5128663. doi:10.1042/bj1230015.

[2] Bathena, SP; Mukherjee, S; Olivera, M; Alnouti, Y. The profile of bile acids and their sulfate metabolites in human urine and serum.. Journal of Chromatography B. 30 December 2013,. 942-943: 53–62. PMID 24212143. doi:10.1016/j.jchromb.2013.10.019.

[3] Russell DW. The enzymes, regulation, and genetics of bile acid synthesis. Annu. Rev. Biochem. 2003, 72: 137–74. PMID 12543708. doi:10.1146/annurev.biochem.72.121801.161712.

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