2-溴-2,3,3-三甲基丁烷

2-溴-2,3,3-三甲基丁烷是一种有机溴化合物,化学式为C7H15Br,它是溴庚烷的同分异构体之一。它可由2,3,3-三甲基-1-丁烯和HBr反应制得。[2]它在液溴中可以进一步溴化,得到1,2,4-三溴-2,3-二(溴甲基)-3-甲基丁烷。[3]在镍配合物催化下,它和苯甲酸酐丙烯酸叔丁酯-溴化镁存在下反应,可以得到β-氧代-α-(2,2,3,3-四甲基丁基)苯丙酸叔丁酯。[4]

2-溴-2,3,3-三甲基丁烷
识别
CAS号 16468-75-0  checkY
性质
化学式 C7H15Br
摩尔质量 179.1 g·mol−1
熔点 149—150 °C(422—423 K)[1]
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。

参考文献

  1. ^ Glen A. Russell, Herbert C. Brown. The Photobromination of Branched-chain Hydrocarbons; the Dark Reaction of Bromine with Tertiary Alkyl Bromides 1,2. Journal of the American Chemical Society. 1955-08, 77 (15): 4025–4030 [2022-05-27]. ISSN 0002-7863. doi:10.1021/ja01620a020. (原始内容存档于2022-05-27) (英语). 
  2. ^ Sebastian Torker, Andre Müller, Peter Chen. Building Stereoselectivity into a Chemoselective Ring-Opening Metathesis Polymerization Catalyst for Alternating Copolymerization. Angewandte Chemie International Edition. 2010-04-15, 49 (22): 3762–3766 [2022-05-27]. doi:10.1002/anie.200906846. (原始内容存档于2022-05-27) (英语). 
  3. ^ Baklan, V. F.; Orlova, R. K.; Yurchenko, A. G. Bromination of branched hydrocarbons in liquid bromine. Ukrainskii Khimicheskii Zhurnal (Russian Edition), 1984. 50 (7): 760-762. ISSN 0041-6045.
  4. ^ Lin Wang, Chuan Wang. Nickel-Catalyzed Three-Component Reductive Alkylacylation of Electron-Deficient Activated Alkenes. Organic Letters. 2020-11-20, 22 (22): 8829–8835 [2022-05-27]. ISSN 1523-7060. doi:10.1021/acs.orglett.0c03210. (原始内容存档于2022-05-27) (英语).