3'-碘甲腺原氨酸

化合物

3'-碘甲状腺原氨酸,英文:3'-Monoiodothyronine,是一种单碘化的甲状腺原氨酸,化学式为C15H14INO4

3'-碘甲状腺原氨酸
Skeletal formula of 3′-monoiodothyronine
Ball-and-stick model of the 3′-monoiodothyronine molecule as a zwitterion
IUPAC名
3′-Iodo-L-thyronine[1]
系统名
(2S)-2-Amino-3-[4-(4-hydroxy-3-iodophenoxy)phenyl]propanoic acid
别名 3′-T1; O-(4-Hydroxy-3-iodophenyl)-L-tyrosine
识别
CAS号 4732-82-5  checkY
PubChem 122056
ChemSpider 108867
SMILES
 
  • C1=CC(=CC=C1C[C@@H](C(=O)O)N)OC2=CC(=C(C=C2)O)I
InChI
 
  • 1/C15H14INO4/c16-12-8-11(5-6-14(12)18)21-10-3-1-9(2-4-10)7-13(17)15(19)20/h1-6,8,13,18H,7,17H2,(H,19,20)/t13-/m0/s1
InChIKey RUIUIJSMLKJUDC-ZDUSSCGKBB
性质
化学式 C15H14INO4
摩尔质量 399.18 g/mol g·mol⁻¹
外观 灰白色针状晶体[2]
熔点 207 °C(分解)[2]
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。

它可以L-甲状腺原氨酸乙胺水溶液、碘化钾为原料反应得到。[2]

参考文献

  1. ^ IUPAC–IUB Joint Commission on Biochemical Nomenclature. Nomenclature and symbolism for amino acids and peptides: Recommendations 1983. European Journal of Biochemistry. 1984, 138 (1): 9–37. PMID 6692818. S2CID 1437908 . doi:10.1111/j.1432-1033.1984.tb07877.x . 
  2. ^ 2.0 2.1 2.2 J. S. Varcoe, W. K. Warburton. 541. The synthesis of thyroxine and related substances. Part XIV. The preparation and chromatography of some iodinated thyronines. Journal of the Chemical Society (Resumed). 1960: 2711 [2023-06-13]. ISSN 0368-1769. doi:10.1039/jr9600002711 (英语).