4-羟基苯乙腈

化合物

4-羟基苯乙腈是一种天然存在的类有机物,化学式为C8H7NO。它是白芥白芥子苷的代谢产物之一。[1]

4-羟基苯乙腈
识别
CAS号 14191-95-8  checkY
PubChem 26548
SMILES
 
  • N#CCC1=CC=C(O)C=C1
性质
化学式 C8H7NO
摩尔质量 133.15 g·mol⁻¹
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。

合成

4-羟基苯乙腈可由4-羟基苯乙酰胺催化脱水制得;[2]或由4-氨基苯乙腈和亚硝酸钠硫酸反应得到。[3]

参考文献

  1. ^ Vladimir Borek, Matthew J. Morra, Ionic Thiocyanate (SCN - ) Production from 4-Hydroxybenzyl Glucosinolate Contained in Sinapis alba Seed Meal, Journal of Agricultural and Food Chemistry 53 (22), 2005-11-01, 53 (22): 8650–8654, doi:10.1021/jf051570r 
  2. ^ Shishuai Ren, Yangyang Wang, Fei Yang, Hongjian Sun, Xiaoyan Li. Dehydration of primary amides to nitriles catalyzed by [CNC]-pincer hydrido cobalt(III) complexes. Catalysis Communications, 2019. 120: 72-75. doi:10.1016/j.catcom.2018.12.002.
  3. ^ Pschorr, R. Synthetic research in the phenanthrene series: Synthesis of pseudo-thebaol. Berichte der Deutschen Chemischen Gesellschaft, 1900. 33: 176-183. doi:10.1002/cber.19000330122.