4-MeO-DMT

化合物

4-MeO-DMT4-甲氧基-N,N-二甲基色胺,英語:4-Methoxy-N,N-dimethyltryptamine,也称为O-甲基脱磷酸裸盖菇素,英語:O-methylpsilocin)是一种色胺衍生物,化学式C13H18N2O,能作为致幻剂,效果弱于5-甲氧基二甲基色胺(5-MeO-DMT)和脱磷酸裸盖菇素(4-HO-DMT)。[1][2][3][4]

4-MeO-DMT
识别信息
  • 2-(4-Methoxy-1H-indol-3-yl)-N,N-dimethylethanamine
CAS号3965-97-7  checkY
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
化学信息
化学式C13H18N2O
摩尔质量218.30 g·mol−1
3D模型(JSmol英语JSmol
  • CN(C)CCC1=CNC2=CC=CC(OC)=C21
  • InChI=1S/C13H18N2O/c1-15(2)8-7-10-9-14-11-5-4-6-12(16-3)13(10)11/h4-6,9,14H,7-8H2,1-3H3 checkY
  • Key:HFYHBTWTJDAYGW-UHFFFAOYSA-N checkY

参考文献

  1. ^ Glennon RA, Young R, Benington F, Morin RD. Hallucinogens as discriminative stimuli: a comparison of 4-OMe DMT and 5-OMe DMT with their methythio counterparts. Life Sciences. February 1982, 30 (5): 465–7. PMID 6801410. doi:10.1016/0024-3205(82)90463-5. 
  2. ^ Kline TB, Benington F, Morin RD, Beaton JM. Structure-activity relationships in potentially hallucinogenic N,N-dialkyltryptamines substituted in the benzene moiety. Journal of Medicinal Chemistry. August 1982, 25 (8): 908–13. PMID 7120280. doi:10.1021/jm00350a005. 
  3. ^ Kline TB, Benington F, Morin RD, Beaton JM, Glennon RA, Domelsmith LN, Houk KN, Rozeboom MD. Structure-activity relationships for hallucinogenic N,N-dialkyltryptamines: photoelectron spectra and serotonin receptor affinities of methylthio and methylenedioxy derivatives. Journal of Medicinal Chemistry. November 1982, 25 (11): 1381–3. PMID 6815326. doi:10.1021/jm00353a021. 
  4. ^ Nichols DE, Glennon RA. Medicinal Chemistry and Structure-Activity Relationships of Hallucinogens, in Hallucinogens, Neurochemical, Behavioral, and Clinical Perspectives (Raven Press 1984), pp 95-142. ISBN 978-0-89004-990-7