N-甲酰基吗啉
化合物
N-甲酰基吗啉是一种有机化合物,化学式为O(C2H4)2NCHO。它是无色的化合物,可用作较高温度下的溶剂。[1]它也是一种甲酰化试剂。[2]
N-甲酰基吗啉 | |
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IUPAC名 Morpholine-4-carbaldehyde | |
别名 | 1-甲酰基吗啉 |
识别 | |
CAS号 | 4394-85-8 ![]() |
PubChem | 20417 |
SMILES |
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InChI |
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InChIKey | LCEDQNDDFOCWGG-UHFFFAOYSA-N |
性质 | |
化学式 | C5H9NO2 |
摩尔质量 | 115.13 g·mol−1 |
外观 | 无色或白色固体 |
密度 | 1.145 g·cm−3(26 °C) |
熔点 | 21 °C(294 K) |
沸点 | 239 °C(512 K) |
危险性 | |
GHS危险性符号![]() | |
GHS提示词 | 警告 |
H-术语 | H317, H319, H335 |
P-术语 | P261, P264, P271, P272, P280, P302+352, P304+340, P305+351+338, P312, P321, P333+313, P337+313, P363, P403+233 |
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。 |
参考文献
- ^ Bipp, H.; Kieczka, H., Formamides, Ullmann's Encyclopedia of Industrial Chemistry, Weinheim: Wiley-VCH, 2005, doi:10.1002/14356007.a12_001.pub2
- ^ George A. Olah; Lena Ohannesian; Massoud Arvanaghi. N-Formylmorpholine: a New and Effective Formylating Agent for the Preparation of Aldehydes and Dialkyl (1-formylalkyl)phosphonates from Grignard or Organolithium Reagents. J. Org. Chem. 1984, 49: 3856–3857. doi:10.1021/jo00194a045.
- ^ Vishal V. Phatake, Ashish A. Mishra, Bhalchandra M. Bhanage. UiO-66 as an efficient catalyst for N-formylation of amines with CO2 and dimethylamine borane as a reducing agent. Inorganica Chimica Acta. 2020-02, 501: 119274 [2020-12-29]. doi:10.1016/j.ica.2019.119274 (英语).