SCH-5472

化合物

SCH-5472是一种含氮有机化合物,分子式C19H23NO,能作为兴奋剂[1],1950年代由先灵葆雅开发[2]

SCH-5472
识别信息
  • 2-benzhydryl-1-methyl-piperidin-3-ol
CAS号20068-90-0((phenylsuccinate))  checkY
PubChem CID
ChemSpider
UNII
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
化学信息
化学式C19H23NO
摩尔质量281.40 g·mol−1
3D模型(JSmol英语JSmol
  • OC(CCCN1C)C1C(C2=CC=CC=C2)C3=CC=CC=C3
  • InChI=1S/C19H23NO/c1-20-14-8-13-17(21)19(20)18(15-9-4-2-5-10-15)16-11-6-3-7-12-16/h2-7,9-12,17-19,21H,8,13-14H2,1H3 ☒N
  • Key:DQNBDZSLMWHFTB-UHFFFAOYSA-N ☒N
合成方式[3]

参考文献

  1. ^ Nodine JH, Bodi T, Slap J, Levy HA, Siegler PE. Preliminary trial of a new stimulant SCH 5472 in ambulatory patients with depression, exhaustion, or hypersomnia syndrome. Antibiotic Medicine & Clinical Therapy. December 1960, 7: 771–6. PMID 13729397. 
  2. ^ US patent 2997478,Walter LA, Sperber N,「Oxygenated Piperidines and Process for their Manufacture」,发行于1961-08-22,指定于Schering 
  3. ^ Walter, L., Springer, C., Kenney, J., Galen, S., & Sperber, N. (1968). Derivatives of 3-Piperidinol as Central Stimulants. Journal of Medicinal Chemistry, 11(4), 792–796. https://doi.org/10.1021/jm00310a612