Template:PBB/613

Breakpoint cluster region
PDB rendering based on 1k1f.
有效结构 PDB 直系同源检索：PDBe, RCSB PDB查询代码列表 1K1F, 2AIN
标识
代号	BCR; ALL; BCR1; CML; D22S11; D22S662; PHL
扩展标识	遗传学：151410 鼠基因：88141 同源基因：3192 ChEMBL: 5146 GeneCards: BCR Gene
EC編號	2.7.11.1
基因本体论描述 分子功能 · protein serine/threonine kinase activity · protein tyrosine kinase activity · Rho guanyl-nucleotide exchange factor activity · GTPase activator activity · protein binding · ATP binding · phospholipid binding · kinase activity · enzyme binding · Rac GTPase activator activity 细胞成分 · cytosol · plasma membrane 生物过程 · protein phosphorylation · signal transduction · small GTPase mediated signal transduction · brain development · actin cytoskeleton organization · negative regulation of cell migration · response to lipopolysaccharide · inner ear morphogenesis · negative regulation of neutrophil degranulation · protein autophosphorylation · platelet-derived growth factor receptor signaling pathway · negative regulation of inflammatory response · positive regulation of phagocytosis · neuromuscular process controlling balance · regulation of small GTPase mediated signal transduction · regulation of cell cycle Sources: Amigo / QuickGO
直系同源体
物种	人类	小鼠
Entrez	613	110279
Ensembl	ENSG00000186716	ENSMUSG00000009681
UniProt	P11274	Q6PAJ1
mRNA序列	NM_004327	NM_001081412
蛋白序列	NP_004318	NP_001074881
基因位置	Chr 22: 23.52 – 23.66 Mb	Chr 10: 75.06 – 75.18 Mb
PubMed查询	[1]	[2]