槟榔次碱
槟榔次碱是一种生物碱,存在于槟榔的果实中[3]。它是一种竞争性GABA摄取抑制剂。有研究称,青柠能够将槟榔碱水解成槟榔次碱[4]。
槟榔次碱 | |
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IUPAC名 1-Methyl-1,2,5,6-tetrahydropyridine-3-carboxylic acid | |
别名 | Methylguvacine; Arecaine; N-Methylguvacine |
识别 | |
CAS号 | 499-04-7 ![]() |
PubChem | 10355 |
ChemSpider | 9928 |
SMILES |
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InChI |
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InChIKey | DNJFTXKSFAMXQF-UHFFFAOYAS |
性质 | |
化学式 | C7H11NO2 |
摩尔质量 | 141.17 g·mol−1 |
熔点 | 232 °C(505 K)(分解)[1] |
沸点 | 104~112 °C(14~16 torr)[2] |
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。 |
参考资料
- ^ "PhysProp" data were obtained from Syracuse Research Corporation of Syracuse, New York (US). Retrieved from SciFinder. [2021-08-15].
- ^ Berichte der Deutschen Chemischen Gesellschaft. Journal of the American Chemical Society. 1880-04, 2 (4) [2022-10-24]. ISSN 0002-7863. doi:10.1021/ja02135a601. (原始内容存档于2022-10-24) (英语).
- ^ Voigt, Valerie; Laug, Linda; Zebisch, Katja; Thondorf, Iris; Markwardt, Fritz; Brandsch, Matthias. Transport of the areca nut alkaloid arecaidine by the human proton-coupled amino acid transporter 1 (hPAT1). Journal of Pharmacy and Pharmacology. 2013-03-12, 65 (4). ISSN 0022-3573. PMID 23488788. doi:10.1111/jphp.12006 (英语).
- ^ Johnston, G. A. R.; Krogsgaard-Larsen, P.; Stephanson, A. Betel nut constituents as inhibitors of γ-aminobutyric acid uptake. Nature. 1975-12, 258 (5536) [2022-10-24]. Bibcode:1975Natur.258..627J. ISSN 0028-0836. PMID 1207742. doi:10.1038/258627a0. (原始内容存档于2022-10-24) (英语).