组氨酸钠

组氨酸钠是一种氨基酸盐,化学式为C6H8N3O2Na。

组氨酸钠
识别
CAS号 1595072-69-7  checkY
23768-86-7(L)  checkY
SMILES
 
  • [Na].O=C(O)C(N)CC1=CN=CN1
性质
化学式 C6H8N3NaO2
摩尔质量 177.14 g·mol−1
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。

制备

组氨酸钠可由组氨酸氢氧化钠反应制得[1]

它和二溴三(4-甲苯基)锑反应,可以得到二(组氨酸)三(4-甲苯基)锑[2]。它和反应,可以得到相应的席夫碱[3]

参考文献

  1. ^ Balaev, A. N.; Okhmanovich, K. A.; Fedorov, V. E. Convenient Four-Step Synthesis of H-Pyr-His-Trp-OH, a Key Tripeptide Intermediate for the Production of Synthetic Gonadoliberin Agonists. Pharmaceutical Chemistry Journal. 2016-06, 50 (3): 192–194. doi:10.1007/s11094-016-1421-2. 
  2. ^ Mushtaq, Rabia; Rauf, Muhammad Khawar; Bond, Marcus; Badshah, Amin; Ali, Muhammad Irshad; Nadhman, Akhtar; Yasinzai, Masoom; Tahir, Muhammad Nawaz. A structural investigation of heteroleptic pentavalent antimonials and their leishmanicidal activity: Synthesis of leishmanicidal heteroleptic pentavalent antimonials. Applied Organometallic Chemistry. 2016-06, 30 (6): 465–472. doi:10.1002/aoc.3456. 
  3. ^ Borisova, Nataliya E.; Gulevich, Tatiana G.; Reshetova, Marina D.; Knizhnikov, Valeri A. Simple and Reliable Protocol for Metal-Free Assembling of the Bibrachial Schiff Bases and Their Reduced Derivatives Bearing Amino Acids or Short Peptide Residues. Synthetic Communications. 2013-01, 43 (3): 345–360. doi:10.1080/00397911.2011.597534.