組氨酸鈉

組氨酸鈉是一種胺基酸鹽,化學式為C6H8N3O2Na。

組氨酸鈉
識別
CAS號 1595072-69-7  checkY
23768-86-7(L)  checkY
SMILES
 
  • [Na].O=C(O)C(N)CC1=CN=CN1
性質
化學式 C6H8N3NaO2
摩爾質量 177.14 g·mol−1
若非註明,所有數據均出自標準狀態(25 ℃,100 kPa)下。

製備

組氨酸鈉可由組氨酸氫氧化鈉反應製得[1]

它和二溴三(4-甲苯基)銻反應,可以得到二(組氨酸)三(4-甲苯基)銻[2]。它和反應,可以得到相應的席夫鹼[3]

參考文獻

  1. ^ Balaev, A. N.; Okhmanovich, K. A.; Fedorov, V. E. Convenient Four-Step Synthesis of H-Pyr-His-Trp-OH, a Key Tripeptide Intermediate for the Production of Synthetic Gonadoliberin Agonists. Pharmaceutical Chemistry Journal. 2016-06, 50 (3): 192–194. doi:10.1007/s11094-016-1421-2. 
  2. ^ Mushtaq, Rabia; Rauf, Muhammad Khawar; Bond, Marcus; Badshah, Amin; Ali, Muhammad Irshad; Nadhman, Akhtar; Yasinzai, Masoom; Tahir, Muhammad Nawaz. A structural investigation of heteroleptic pentavalent antimonials and their leishmanicidal activity: Synthesis of leishmanicidal heteroleptic pentavalent antimonials. Applied Organometallic Chemistry. 2016-06, 30 (6): 465–472. doi:10.1002/aoc.3456. 
  3. ^ Borisova, Nataliya E.; Gulevich, Tatiana G.; Reshetova, Marina D.; Knizhnikov, Valeri A. Simple and Reliable Protocol for Metal-Free Assembling of the Bibrachial Schiff Bases and Their Reduced Derivatives Bearing Amino Acids or Short Peptide Residues. Synthetic Communications. 2013-01, 43 (3): 345–360. doi:10.1080/00397911.2011.597534.