甘露聚糖结合凝集素

甘露聚糖结合凝集素(英语:Mannose-binding lectin,缩写MBL,也被称为甘露糖结合蛋白甘露聚糖结合蛋白,英语:mannan-binding protein,缩写MBP)是一种在先天免疫系统中起作用的凝集素[1][2]

Mannose-binding lectin (protein C) 2, soluble
甘露糖结合凝集素(蛋白C)2,可溶
PDB rendering based on 1hup.
有效结构
PDB 直系同源检索:PDBe, RCSB
标识
代号 MBL2; COLEC1; HSMBPC; MBL; MBL2D; MBP; MBP-C; MBP1; MBPD
扩展标识 遗传学154545 鼠基因96924 同源基因110436 ChEMBL: 1795113 GeneCards: MBL2 Gene
RNA表达模式
更多表达数据
直系同源体
物种 人类 小鼠
Entrez 4153 17195
Ensembl ENSG00000165471 ENSMUSG00000024863
UniProt P11226 P41317
mRNA序列 NM_000242 NM_010776
蛋白序列 NP_000233 NP_034906
基因位置 Chr 10:
54.53 – 54.53 Mb
Chr 19:
30.23 – 30.24 Mb
PubMed查询 [1] [2]

外部连接

参考文献

  1. ^ Fraser IP, Koziel H, Ezekowitz RA. The serum mannose-binding protein and the macrophage mannose receptor are pattern recognition molecules that link innate and adaptive immunity.. Semin. Immunol. 1998, 10 (5): 363–72. PMID 9799711. doi:10.1006/smim.1998.0141. 
  2. ^ Worthley DL, Bardy PG, Mullighan CG. Mannose-binding lectin: biology and clinical implications.. Internal medicine journal. 2005, 35 (9): 548–55. PMID 16105157. doi:10.1111/j.1445-5994.2005.00908.x.