2-吡啶甲酸苄酯
2-吡啶甲酸苄酯是一种有机化合物,化学式为C13H11NO2。它可由2-吡啶甲酰氯和苯甲醇在三乙胺存在下反应制得。[3]它和4-氯溴苄反应,可以得到4-氯苄基吡啶𬭩-2-甲酸苄酯溴化物。[2]
2-吡啶甲酸苄酯 | |
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别名 | 吡啶-2-甲酸苯甲酯 |
识别 | |
CAS号 | 71653-37-7 |
SMILES |
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性质 | |
化学式 | C13H11NO2 |
摩尔质量 | 213.23 g·mol−1 |
外观 | 无色油状物[1][2] |
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。 |
参考文献
- ^ Raghunath Reddy Anugu, Sailu Munnuri, and John R. Falck. Picolinate-Directed Arene meta-C–H Amination via FeCl3 Catalysis. J. Am. Chem. Soc. 2020, 142, 11, 5266–5271. doi:10.1021/jacs.9b13753.
- ^ 2.0 2.1 Zhi Yang, Hanlin Chen, Linxi Wan, Xinyi Feng, Lingshuang Ma, Pei Tang, Fen-Er Chen. Sustainable synthesis of long-acting local anesthetics ropivacaine and levobupivacaine under batch and continuous flow via asymmetric hydrogenation. Org. Chem. Front. 2024. 11. 2891-2896. doi:10.1039/D4QO00072B.
- ^ Ju Yuel Baek, Yong-Joo Shin, Heung Bae Jeon, Kwan Soo Kim. Picolinyl group as an efficient alcohol protecting group: cleavage with Zn(OAc)2·2H2O under a neutral condition. Tetrahedron Letters. 2005. 46 (31): 5143-5147. doi:10.1016/j.tetlet.2005.05.125.