4-肼基吡啶

化合物

4-肼基吡啶是一种有机化合物,化学式为C5H7N3,它可由4-氯吡啶水合肼1-丙醇中回流得到。[1]它和1,4-二(溴甲基)苯反应,得到吡啶烷基化的双季铵盐[2]它和乙酰丙酮反应,可以得到4-(3,5-二甲基-1H-吡唑基)吡啶。[3]

4-肼基吡啶
别名 4-吡啶肼
识别
CAS号 27256-91-3  checkY
性质
化学式 C5H7N3
摩尔质量 109.13 g·mol−1
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。

参考文献

  1. ^ Sülünay Parlar, Yalçın Erzurumlu, Recep Ilhan, Petek Ballar Kırmızıbayrak, Vildan Alptüzün, Ercin Erciyas. Synthesis and evaluation of pyridinium-hydrazone derivatives as potential antitumoral agents. Chemical Biology & Drug Design. 2018-07, 92 (1): 1198–1205 [2022-03-05]. doi:10.1111/cbdd.13177. (原始内容存档于2022-03-05) (英语). 
  2. ^ Arturo Blanco-Gómez, Iago Neira, José L. Barriada, Manuel Melle-Franco, Carlos Peinador, Marcos D. García. Thinking outside the “Blue Box”: from molecular to supramolecular pH-responsiveness. Chemical Science. 2019, 10 (46): 10680–10686 [2022-03-05]. ISSN 2041-6520. PMC 7069232 . PMID 32206250. doi:10.1039/C9SC04489B (英语). 
  3. ^ Badescu, Valentina O.; Camp, Anne Marie; Clark, Barry Peter; Cohen, Michael Philip; Filla, Sandra Ann; Gallagher, Peter Thaddeus; Hellman, Sarah Lynne; Mazanetz, Michael Philip; Pineiro-Nunez, Marta Maria; Schaus, John Mehnert; Spinazze, Patrick Gianpietro; Whatton, Maria Ann. 2-[4-(Pyrazol-4-ylalkyl)​piperazin-1-yl]-3-phenylpiperazines and pyridines and 3-[4-(pyrazol-4-ylalkyl)​piperazin-1-yl]-2-phenylpyridines as 5-HT7 receptor antagonist and their preparation and use in the treatment of migraine, persistent pain and anxiety. 2008 WO 2008141020 A1.