BCP-1细胞
BCP-1 (BCP-1 Cells) 是淋巴瘤克隆细胞系,最初是分离于人类免疫缺乏病毒呈阴性的男性原发性体液淋巴瘤(PEL)患者的外周血单核细胞[1]。 BCP-1细胞对卡波西氏肉瘤疱疹病毒 (KSHV) 呈阳性[2],但是对人类疱疹病毒第四型呈阴性。该细胞系目前广泛应用于KSHV血清学测定、流行病学研究及其他的KSHV实验研究,例如在TPA潜伏期或KSHV ORF 50异位表达引起的KSHV重新激活。
参考资料
- ^ Boshoff, C; Gao, SJ; Healy, LE; Matthews, S; Thomas, AJ; Coignet, L; Warnke, RA; Strauchen, JA; Matutes, E; Kamel, OW; Moore, PS; Weiss, RA; Chang, Y. Establishing a KSHV+ cell line (BCP-1) from peripheral blood and characterizing its growth in Nod/SCID mice.. Blood. 1998-03-01, 91 (5): 1671–9 [2019-11-28]. PMID 9473233.
- ^ Gao, SJ; Kingsley, L; Li, M; Zheng, W; Parravicini, C; Ziegler, J; Newton, R; Rinaldo, CR; Saah, A; Phair, J; Detels, R; Chang, Y; Moore, PS. KSHV antibodies among Americans, Italians and Ugandans with and without Kaposi's sarcoma.. Nature medicine. 1996-08, 2 (8): 925–8 [2019-11-28]. PMID 8705864. doi:10.1038/nm0896-925.