匹戊肼

化合物

匹戊肼(英语:Pivhydrazine)是家族的一种不可逆、非选择性单胺氧化酶抑制剂。它曾在1960年代被用作抗抑郁药,但现已停产。[1][2][3]

匹戊肼
临床资料
其他名称Angorvid, Betamezid, Neomarsilid, Pivazide, Pivhydrazine
给药途径Oral
ATC码
  • 未分配
法律规范状态
法律规范
  • 处方药(-only)
识别信息
  • N'-benzyl-2,2-dimethyl-propanehydrazide
CAS号306-19-4  checkY
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
ECHA InfoCard100.005.620 编辑维基数据链接
化学信息
化学式C12H18N2O
摩尔质量206.29 g·mol−1
  • InChI=1S/C12H18N2O/c1-12(2,3)11(15)14-13-9-10-7-5-4-6-8-10/h4-8,13H,9H2,1-3H3,(H,14,15) checkY
  • Key:FWWDFDMCZLOXQI-UHFFFAOYSA-N checkY

参见

参考资料

  1. ^ Herman ZS, Sokola A, Lenartowicz H, Zieliński M, Depta L. The influence of antidepressive drugs on the level of acetylcholine and on the acetylcholinesterase activity in the brain of rats. Polish Journal of Pharmacology and Pharmacy. May–June 1976, 28 (4): 313–21. OCLC 1586290. PMID 981020. 
  2. ^ Bolton GC, Griffiths LA. The metabolic disposition of [14C]pivhydrazine, [14C]mebanazine, and [14C]benzylhydrazine in the rat. Drug Metabolism and Disposition. November–December 1979, 7 (6): 388–92 [2024-05-13]. OCLC 1784380. PMID 43225. (原始内容存档于2019-08-05). 
  3. ^ Mikhaĭlova TV, Gilev AP, Khavronina-Gureeva ZP. [Central effects of betamezide]. Farmakologiia I Toksikologiia. 1969, 32 (6): 652–6. OCLC 1568906. PMID 5381593 (Russian).