呋拉茶碱

化合物

呋拉茶碱(英语:Furafylline)是一种含氮有机化合物,分子式C12H12N4O3,可看作甲基茶碱衍生物,能作为CYP1A2酶抑制剂[1]

呋拉茶碱
临床资料
ATC码
  • 未分配
识别信息
  • 3-(Furan-2-ylmethyl)-1,8-dimethyl-7H-purine-2,6-dione
CAS号80288-49-9  checkY
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
化学信息
化学式C12H12N4O3
摩尔质量260.25 g·mol−1
3D模型(JSmol英语JSmol
  • Cc1[nH]c2c(n1)n(c(=O)n(c2=O)C)Cc3ccco3
  • InChI=1S/C12H12N4O3/c1-7-13-9-10(14-7)16(6-8-4-3-5-19-8)12(18)15(2)11(9)17/h3-5H,6H2,1-2H3,(H,13,14) ☒N
  • Key:KGQZGCIVHYLPBH-UHFFFAOYSA-N ☒N

参考文献

  1. ^ Sesardic D, Boobis AR, Murray BP, Murray S, Segura J, de la Torre R, Davies DS. Furafylline is a potent and selective inhibitor of cytochrome P450IA2 in man. British Journal of Clinical Pharmacology. June 1990, 29 (6): 651–63. PMC 1380167 . PMID 2378786. doi:10.1111/j.1365-2125.1990.tb03686.x.