炔孕酮

炔孕酮
临床资料
商品名（英语：Drug nomenclature）	Proluton C, Pranone, others
其他名称	Ethinyltestosterone; Ethynyltestosterone; Pregneninolone; Anhydrohydroxyprogesterone; Etisteron; Pregnin; Ethindrone
给药途径	口服给药，口腔黏膜吸收
药物类别（英语：Drug class）	Progestin; Progestogen; Androgen; Anabolic steroid
ATC码	G03DC04 (WHO) ;
药物动力学数据
代谢产物	• 5α-双氢炔孕酮（英语：5α-Dihydroethisterone）
识别信息
	IUPAC命名法 (8R,9S,10R,13R,14S,17R)-17-Ethynyl-17-hydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one; ;
CAS号	434-03-7
PubChem CID	5284557;
ChemSpider	4447612 ;
UNII	P201BVY1MJ;
ChEBI	CHEBI:34749 ;
ChEMBL	ChEMBL241694 ;
CompTox Dashboard（英语：CompTox Chemicals Dashboard） (EPA)	DTXSID2023016 ;
ECHA InfoCard	100.006.452
化学信息
化学式	C21H28O2
摩尔质量	312.446 g/mol
3D模型（JSmol（英语：JSmol））	交互式图像;
	SMILES C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CC[C@]4(C#C)O)C;
	InChI InChI=1S/C21H28O2/c1-4-21(23)12-9-18-16-6-5-14-13-15(22)7-10-19(14,2)17(16)8-11-20(18,21)3/h1,13,16-18,23H,5-12H2,2-3H3/t16-,17+,18+,19+,20+,21+/m1/s1 ; Key:CHNXZKVNWQUJIB-CEGNMAFCSA-N ;

炔孕酮（英语：Ethisterone），也有称为乙炔睾酮（英语：ethinyltestosterone）、孕炔醇酮（英语：pregneninolone，商品名：Proluton C 或 Pranone等）是一种黄体制剂药物，过去被用于治疗一些妇科疾病，但现在已不再使用^[3]^[4]^[5]。

参考文献

^ University of California (1868-1952). Hospital Formulary and Compendium of Useful Information. University of California Press. 1952: 49–. GGKEY:2UAAZRZ5LN0.
^ Lemus AE, Enríquez J, García GA, Grillasca I, Pérez-Palacios G. 5alpha-reduction of norethisterone enhances its binding affinity for androgen receptors but diminishes its androgenic potency. J. Steroid Biochem. Mol. Biol. 1997, 60 (1–2): 121–9. PMID 9182866. doi:10.1016/s0960-0760(96)00172-0.
^ Swyer GI. Oral Hormonal Therapy for Menstrual Disorders. Br Med J. 1950, 1 (4654): 626–34. PMC 2037145  . PMID 20787798. doi:10.1136/bmj.1.4654.626.
^ Dr. Ian Morton; I.K. Morton; Judith M. Hall. Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Science & Business Media. 31 October 1999: 115–. ISBN 978-0-7514-0499-9.
^ 存档副本. [2019-06-24]. （原始内容存档于2019-06-24）.

[UCPress1952-1] University of California (1868-1952). Hospital Formulary and Compendium of Useful Information. University of California Press. 1952: 49–. GGKEY:2UAAZRZ5LN0.

[pmid9182866-2] Lemus AE, Enríquez J, García GA, Grillasca I, Pérez-Palacios G. 5alpha-reduction of norethisterone enhances its binding affinity for androgen receptors but diminishes its androgenic potency. J. Steroid Biochem. Mol. Biol. 1997, 60 (1–2): 121–9. PMID 9182866. doi:10.1016/s0960-0760(96)00172-0.

[pmid20787798-3] Swyer GI. Oral Hormonal Therapy for Menstrual Disorders. Br Med J. 1950, 1 (4654): 626–34. PMC 2037145  . PMID 20787798. doi:10.1136/bmj.1.4654.626.

[MortonHall1999-4] Dr. Ian Morton; I.K. Morton; Judith M. Hall. Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Science & Business Media. 31 October 1999: 115–. ISBN 978-0-7514-0499-9.

[Drugs.com-5] 存档副本. [2019-06-24]. （原始内容存档于2019-06-24）.

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