转录激活因子

转录激活因子(英文：Activator)是一种蛋白质转录因子，可增加一个基因或一组基因的转录。^[1]转录激活因子被认为对基因表达具有积极的调控作用，因为它们具有促进基因转录的功能，在某些情况下是基因转录所必需的。^[1]^[2]^[3]^[4]大多数激活因子是与增强子和启动子近端元件结合的DNA结合蛋白。^[1]与激活因子结合的DNA位点称为“激活因子结合位点”。^[3]激活因子与一般转录机制发生蛋白质相互作用的部分称为“活化区”或“活化域”。^[1]

参考资料

^ ^1.0 ^1.1 ^1.2 ^1.3 Ma, Jun. Transcriptional activators and activation mechanisms. Protein & Cell. 2011, 2 (11): 879–888 [2021-03-17]. ISSN 1674-8018. PMC 4712173  . PMID 22180087. doi:10.1007/s13238-011-1101-7. （原始内容存档于2021-05-15） –通过PubMed.
^ Alberts, Bruce; Johnson, Alexander; Lewis, Julian; Morgan, David; Raff, Martin; Roberts, Keith; Walter, Peter. Molecular Biology of the Cell Sixth. New York, NY: Garland Science. 2015: 373–392 [2021-03-17]. ISBN 978-0-8153-4432-2. OCLC 887605755. （原始内容存档于2021-04-20）.
^ ^3.0 ^3.1 Madigan, Michael T; Bender, Kelly S; Buckley, Daniel H; Sattley, Matthew W; Stahl, David A. Brock Biology of Microorganisms Fifteenth. NY, NY: Pearson. 2018: 174–179. ISBN 978-0-13-426192-8. OCLC 958205447.
^ Griffiths, Anthony J.F.; Gelbart, William M.; Miller, Jeffrey H.; Lewontin, Richard C. The Basics of Prokaryotic Transcriptional Regulation. Modern Genetic Analysis. 1999 –通过NCBI （英语）.

[:0-1] 1.0 ^1.1 ^1.2 ^1.3 Ma, Jun. Transcriptional activators and activation mechanisms. Protein & Cell. 2011, 2 (11): 879–888 [2021-03-17]. ISSN 1674-8018. PMC 4712173  . PMID 22180087. doi:10.1007/s13238-011-1101-7. （原始内容存档于2021-05-15） –通过PubMed.

[:1-2] Alberts, Bruce; Johnson, Alexander; Lewis, Julian; Morgan, David; Raff, Martin; Roberts, Keith; Walter, Peter. Molecular Biology of the Cell Sixth. New York, NY: Garland Science. 2015: 373–392 [2021-03-17]. ISBN 978-0-8153-4432-2. OCLC 887605755. （原始内容存档于2021-04-20）.

[:2-3] 3.0 ^3.1 Madigan, Michael T; Bender, Kelly S; Buckley, Daniel H; Sattley, Matthew W; Stahl, David A. Brock Biology of Microorganisms Fifteenth. NY, NY: Pearson. 2018: 174–179. ISBN 978-0-13-426192-8. OCLC 958205447.

[:3-4] Griffiths, Anthony J.F.; Gelbart, William M.; Miller, Jeffrey H.; Lewontin, Richard C. The Basics of Prokaryotic Transcriptional Regulation. Modern Genetic Analysis. 1999 –通过NCBI （英语）.

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