细胞色素P450 1A2(英语:Cytochrome P450 1A2 (缩写为CYP1A2),是细胞色素P450混合功能氧化家族的一员,参与体内异生物质的代谢[1]CYP1A2酶由人类CYP1A2基因编码。[2]

Cytochrome P450, family 1, subfamily A, polypeptide 2
PDB根据2hi4所绘制的渲染图
有效结构
PDB 直系同源检索:PDBe, RCSB
标识
代号 CYP1A2; CP12; P3-450; P450(PA)
扩展标识 遗传学124060 鼠基因88589 同源基因68082 ChEMBL: 3356 GeneCards: CYP1A2 Gene
EC编号 1.14.14.1
RNA表达模式
更多表达数据
直系同源体
物种 人类 小鼠
Entrez 1544 13077
Ensembl ENSG00000140505 ENSMUSG00000032310
UniProt P05177 P00186
mRNA序列 NM_000761 NM_009993
蛋白序列 NP_000752 NP_034123
基因位置 Chr 15:
74.75 – 74.76 Mb
Chr 9:
57.68 – 57.68 Mb
PubMed查询 [1] [2]

引用

  1. ^ Nelson DR, Zeldin DC, Hoffman SM, Maltais LJ, Wain HM, Nebert DW. Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants. Pharmacogenetics. January 2004, 14 (1): 1–18. PMID 15128046. doi:10.1097/00008571-200401000-00001. 
  2. ^ Jaiswal AK, Nebert DW, McBride OW, Gonzalez FJ. Human P(3)450: cDNA and complete protein sequence, repetitive Alu sequences in the 3' nontranslated region, and localization of gene to chromosome 15. J. Exp. Pathol. 1987, 3 (1): 1–17. PMID 3681487. 

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