11-脫氫皮質酮
化合物
11-脫氫皮質酮(英語:11-Dehydrocorticosterone,縮寫11-DHC,或稱為17-脫氧可的松,17-deoxycortisone,21-羥基孕-4-烯-3,11,20-三酮,21-hydroxypregn-4-ene-3,11,20-trione)是一種有機化合物,化學式為C21H28O4,是一種內源性的鹽皮質激素[1]。
11-脫氫皮質酮 | |
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IUPAC名 21-Hydroxypregn-4-ene-3,11,20-trione | |
系統名 (1S,3aS,3bS,9aR,9bS,11aS)-1-(Hydroxyacetyl)-9a,11a-dimethyl-2,3,3a,3b,4,5,8,9,9a,9b,11,11a-dodecahydro-1H-cyclopenta[a]phenanthrene-7,10-dione | |
別名 | 11-DHC; 11-Oxocorticosterone; 17-Deoxycortisone |
識別 | |
CAS號 | 72-23-1 |
PubChem | 5311364 |
ChemSpider | 4470861 |
SMILES |
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ChEBI | 78600 |
性質 | |
化學式 | C21H28O4 |
摩爾質量 | 344.44 g·mol−1 |
若非註明,所有數據均出自標準狀態(25 ℃,100 kPa)下。 |
參考文獻
- ^ Harno, E; Cottrell, EC; Keevil, BG; DeSchoolmeester, J; Bohlooly-Y, M; Andersén, H; Turnbull, AV; Leighton, B; White, A. 11-Dehydrocorticosterone causes metabolic syndrome, which is prevented when 11β-HSD1 is knocked out in livers of male mice.. Endocrinology. 2013-10, 154 (10): 3599–609. PMID 23832962. doi:10.1210/en.2013-1362.