ERV-Fc是一類內源性反轉錄病毒家族[1],廣泛存在於真獸類基因組[2],由3000萬年至1500萬年間不斷感染真獸類的γ-逆轉錄病毒整合而來,此病毒與現在的小鼠白血病病毒英語Murine leukemia virus貓白血病病毒(FeLV)關係最接近[3]靈長類特別是人類基因組中有兩段ERV-Fc[4],分別是位於X染色體的HERV-Fc1和位於7號染色體的HERV-Fc2,代表了兩次γ-逆轉錄病毒整合事件[5]

各種內源性反轉錄病毒的分類關係,ERV-Fc屬於Class I,與ERV-H關係最為接近

參考文獻

  1. ^ Scientists uncover history of ancient viruses as far back as 30 million years ago. phys.org. [2023-01-06]. (原始內容存檔於2023-01-18) (英語). 
  2. ^ Origin and recent expansion of an endogenous gammaretroviral lineage in domestic and wild canids. [2023-01-06]. (原始內容存檔於2023-01-06). 
  3. ^ Page, Geology; Page, Geology. Scientists uncover history of ancient viruses as far back as 30 million years ago. Geology Page. 2016-03-08 [2023-01-06]. (原始內容存檔於2023-01-06). 
  4. ^ Tracking interspecies transmission and long-term evolution of an ancient retrovirus using the genomes of modern mammals頁面存檔備份,存於網際網路檔案館), by William E Diehl, Nirali Patel, Kate Halm, Welkin E Johnson. Boston College, United States. Areas: evolutionary biology, microbiology, infectious disease. Research Article Mar 8, 2016
  5. ^ Characterization of the low-copy HERV-Fc family: evidence for recent integrations in primates of elements with coding envelope genes頁面存檔備份,存於網際網路檔案館), by Laurence Bénit, Alexandra Calteau, Thierry Heidmann. Virology, volume 312, issue 1, 20 July 2003, pages 159-168

外部連結