豬膽酸

豬膽酸
別名	γ-Muricholic acid; Iocholic acid; 3α,6α,7α-Trihydroxy-5β-cholan-24-oic acid
識別
CAS號	547-75-1
PubChem	92805
SMILES	C[C@H](CCC(=O)O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2[C@@H]([C@@H]([C@H]4[C@@]3(CC[C@H](C4)O)C)O)O)C;
ChEBI	81244
KEGG	C17649
性質
化學式	C24H40O5
摩爾質量	408.57 g·mol−1
	若非註明，所有數據均出自標準狀態（25 ℃，100 kPa）下。

豬膽酸（英語：Hyocholic acid，也被稱為3α,6α,7α-三羥基-5β-膽烷-24-羧酸，3α,6α,7α-trihydroxy-5β-cholan-24-oic acid）是豬膽汁酸的主要成分^[1]，在人類膽汁酸中有很低的濃度^[2]^[3]。豬膽酸和人類膽汁酸的主要成分之一膽酸的不同在於第三個羥基基團位於6-號碳原子的α-位而不是12α位。人類膽汁酸的另一種主要成分鵝去氧膽酸則既沒有6-號位也沒有12-號位的羥基基團。另外，豬膽酸也和大鼠的鼠膽酸不同，α和β鼠膽酸的6號位都為6β-羥基。

參考文獻

^ Haslewood, GA. Bile salts of germ-free domestic fowl and pigs.. The Biochemical Journal. June 1971, 123 (1): 15–8. PMC 1176895  . PMID 5128663. doi:10.1042/bj1230015.
^ Bathena, SP; Mukherjee, S; Olivera, M; Alnouti, Y. The profile of bile acids and their sulfate metabolites in human urine and serum.. Journal of Chromatography B. 30 December 2013,. 942-943: 53–62. PMID 24212143. doi:10.1016/j.jchromb.2013.10.019.
^ Russell DW. The enzymes, regulation, and genetics of bile acid synthesis. Annu. Rev. Biochem. 2003, 72: 137–74. PMID 12543708. doi:10.1146/annurev.biochem.72.121801.161712.

[1] Haslewood, GA. Bile salts of germ-free domestic fowl and pigs.. The Biochemical Journal. June 1971, 123 (1): 15–8. PMC 1176895  . PMID 5128663. doi:10.1042/bj1230015.

[2] Bathena, SP; Mukherjee, S; Olivera, M; Alnouti, Y. The profile of bile acids and their sulfate metabolites in human urine and serum.. Journal of Chromatography B. 30 December 2013,. 942-943: 53–62. PMID 24212143. doi:10.1016/j.jchromb.2013.10.019.

[3] Russell DW. The enzymes, regulation, and genetics of bile acid synthesis. Annu. Rev. Biochem. 2003, 72: 137–74. PMID 12543708. doi:10.1146/annurev.biochem.72.121801.161712.

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