2-羥基異己酸

化合物

2-羥基異己酸(英語:2-Hydroxyisocaproic acid,縮寫HICA,也稱為 閃白酸,英語:leucic acid)是支鏈氨基酸亮氨酸代謝產物[1]。HICA經常作為一種所謂的肌肉增強劑出售[2],同時也能作為殺真菌劑使用[2]。HICA能夠增加誘導性肌肉萎縮大鼠的蛋白質生物合成和肌肉質量[3]

2-羥基異己酸
IUPAC名
2-Hydroxy-4-methylpentanoic acid
別名 2-羥基-4-甲基戊酸、閃白酸
識別
CAS號 498-36-2  checkY
PubChem 92779
ChemSpider 83753
SMILES
 
  • CC(C)CC(C(=O)O)O
InChI
 
  • 1/C6H12O3/c1-4(2)3-5(7)6(8)9/h4-5,7H,3H2,1-2H3,(H,8,9)
InChIKey LVRFTAZAXQPQHI-UHFFFAOYAQ
性質
化學式 C6H12O3
摩爾質量 132.16 g·mol−1
若非註明,所有數據均出自標準狀態(25 ℃,100 kPa)下。

參考資料

  1. ^ Investigation of the presence of β-hydroxy-β-methylbutyric acid and α-hydroxyisocaproic acid in bovine whole milk and fermented dairy products by a validated liquid chromatography-mass spectrometry method.. Journal of Agricultural and Food Chemistry. February 2014, 62 (7): 1506–11. PMID 24495238. doi:10.1021/jf500026s. 
  2. ^ 2.0 2.1 2-hydroxyisocaproic acid is fungicidal for Candida and Aspergillus species.. Mycoses. April 2014, 57 (4): 214–21. PMID 24125484. doi:10.1111/myc.12145. 
  3. ^ Chronic α-hydroxyisocaproic acid treatment improves muscle recovery after immobilization-induced atrophy.. American Journal of Physiology. August 2013, 305 (3): E416–28. PMID 23757407. doi:10.1152/ajpendo.00618.2012.