PNU-91356A

化合物

PNU-91356A(也稱為U-91356)是一種含氮有機化合物,分子式C13H17N3O,可作為多巴胺受體D2的選擇性強效激動劑[1],對多巴胺受體D3D4和5-HT1A受體親和力較低[2]

PNU-91356A
臨床資料
ATC碼
  • 未分配
識別資訊
  • (10R)-10-(propylamino)-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-2-one
CAS號152886-85-6  checkY
PubChem CID
UNII
CompTox Dashboard英語CompTox Chemicals Dashboard (EPA)
化學資訊
化學式C13H17N3O
摩爾質量231.30 g·mol−1
3D模型(JSmol英語JSmol
  • CCCNC1CC2=C3C(=CC=C2)NC(=O)N3C1
  • InChI=1S/C13H17N3O/c1-2-6-14-10-7-9-4-3-5-11-12(9)16(8-10)13(17)15-11/h3-5,10,14H,2,6-8H2,1H3,(H,15,17)/t10-/m1/s1
  • Key:XTWUNLMHXDDOMD-SNVBAGLBSA-N

參考文獻

  1. ^ Moon MW, Morris JK, Heier RF, Hsi RS, Manis MO, Royer ME, et al. Medicinal chemistry of imidazoquinolinone dopamine receptor agonists. Drug Design and Discovery. 1993, 9 (3–4): 313–22. PMID 8104520. 
  2. ^ Piercey MF, Moon MW, Sethy VH, Schreur PJ, Smith MW, Tang AH, Von Voigtlander PF. Pharmacology of U-91356A, an agonist for the dopamine D2 receptor subtype. European Journal of Pharmacology. December 1996, 317 (1): 29–38. PMID 8982716. doi:10.1016/s0014-2999(96)00695-4. 

外部連結