乙硫酰丙喹

化合物

乙硫酰丙喹是源自四氢异喹啉α2-肾上腺素能受体激动剂。[1] 它具有正肌力效应,在治疗慢性心力衰竭中有潜在用途。[2]

乙硫酰丙喹
临床资料
其他名称Esproquine
法律规范状态
法律规范
  • Investigational
识别信息
  • 2-(3-Ethylsulfinylpropyl)-3,4-dihydro-1H-isoquinoline
CAS号37517-33-2
PubChem CID
UNII
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
化学信息
化学式C14H21NOS
摩尔质量251.39 g·mol−1
3D模型(JSmol英语JSmol
  • O=S(CC)CCCN1CC=2C=CC=CC2CC1

参考资料

  1. ^ Gray AP, Shiley RH. Preparation and cardiovascular actions of a group of tetrahydroisoquinoline derivatives. Journal of Medicinal Chemistry. July 1973, 16 (7): 859–61. PMID 4146907. doi:10.1021/jm00265a028. 
  2. ^ Kotelanski B, Grozmann RJ, Cohn JN. Positive inotropic effect of oral esproquin in normal subjects. Clinical Pharmacology and Therapeutics. 1973, 14 (3): 427–33. PMID 4698571. S2CID 46266823. doi:10.1002/cpt1973143427.