噻嗪类利尿剂
噻嗪类利尿剂(英语:thiazides)是利尿剂的一类。此类药物可抑制氯化钠在远端曲小管的再吸收。这些药会作用在远端曲小管的细胞管腔膜上,竞争性拮抗顶端(管腔)膜上的钠氯共同运送蛋白[1]。
作用机转
药物
- 氢氯噻嗪(hydrochlorothiazide,HCTZ,HCT 或 HZT)
- Bendroflumethiazide
- Benzthiazide
- Chlorthalidone
- Chlorothiazide
- Hydroflumethiazide
- Polythiazide
- Trichlormethiazide
- Cyclopenthiazide
- Methyclothiazide
- Cyclothiazide
- Mebutizide
- Altizide
- Epitizide
参考资料
- ^ David E. Golan, Armen H. Tashjian, Jr., Ehrin J. Armstrong, April W. Armstrong. Principles of Pharmacology: The Pathophysiologic Basis of Drug Therapy, 3rd edition. Wolters Kluwer Health. 2012. ISBN 978-1608312702.
外部链接
- Diagram at cvpharmacology.com(页面存档备份,存于互联网档案馆)
- "10 Different Types Of Diuretics" by Tom Pisarski