7,8,3'-三羟基黄酮
化合物
7,8,3'-三羟基黄酮（英语：7,8,3′-Trihydroxyflavone，缩写为7,8,3'-THF）是一种黄酮类化合物，7,8-二羟基黄酮的衍生物，可作为脑源性神经营养因子受体TrkB的小分子激动剂[1][2]。
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| 其他名称 | 7,8,3'-THF |
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| 识别信息 | |
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| CAS号 | 137502-84-2 |
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| 化学信息 | |
| 化学式 | C15H10O5 |
| 摩尔质量 | 270.24 g·mol−1 |
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参考文献
- ^ Liu X, Chan CB, Jang SW, Pradoldej S, Huang J, He K, et al. A synthetic 7,8-dihydroxyflavone derivative promotes neurogenesis and exhibits potent antidepressant effect. Journal of Medicinal Chemistry. December 2010, 53 (23): 8274–86. PMC 3150605
. PMID 21073191. doi:10.1021/jm101206p.
- ^ Yu Q, Chang Q, Liu X, Gong S, Ye K, Lin X. 7,8,3'-Trihydroxyflavone, a potent small molecule TrkB receptor agonist, protects spiral ganglion neurons from degeneration both in vitro and in vivo. Biochemical and Biophysical Research Communications. June 2012, 422 (3): 387–92. PMC 3388121 . PMID 22575512. doi:10.1016/j.bbrc.2012.04.154.
