卤米松

糖皮质激素

卤米松是一种皮质类固醇,可用于治疗银屑病[1]以及非感染性急性湿疹皮炎类皮肤病[2]

卤米松
临床资料
AHFS/Drugs.com国际药品名称
ATC码
识别信息
  • (6α,11β,16α)-2-chloro-6,9-difluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
CAS号50629-82-8  checkY
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
ECHA InfoCard100.051.496 编辑维基数据链接
化学信息
化学式C22H27ClF2O5
摩尔质量444.90 g·mol−1
3D模型(JSmol英语JSmol
  • O=C(CO)[C@]3(O)[C@]2(C[C@H](O)[C@]4(F)[C@@]/1(\C(=C/C(=O)C(\Cl)=C\1)[C@@H](F)C[C@H]4[C@@H]2C[C@H]3C)C)C
  • InChI=1S/C22H27ClF2O5/c1-10-4-11-12-5-15(24)13-6-16(27)14(23)7-19(13,2)21(12,25)17(28)8-20(11,3)22(10,30)18(29)9-26/h6-7,10-12,15,17,26,28,30H,4-5,8-9H2,1-3H3/t10-,11+,12+,15+,17+,19+,20+,21+,22+/m1/s1 ☒N
  • Key:GGXMRPUKBWXVHE-MIHLVHIWSA-N ☒N

参考文献

  1. ^ Galbiati, G; Bonfacini, V; Candiani, F. Halometasone cream by day and halometasone ointment at night for the treatment of patients with chronic psoriasis vulgaris. The Journal of international medical research. 1983,. 11 Suppl 1: 31–3. PMID 6339290. 
  2. ^ Yawalkar, SJ; MacArol, V; Montanari, C. An overview of international clinical trials with halometasone cream. The Journal of international medical research. 1983,. 11 Suppl 1: 1–7. PMID 6339286.