PRO-LAD

化合物

PRO-LAD是一种有机化合物,化学式为C22H29N3O,为迷幻药物麦角酸二乙酰胺(LSD)的同系物,最早由亚历山大·舒尔金在其著作《TiHKAL:延续英语TiHKAL》(TIHKAL: The Continuation)中提出[2]

PRO-LAD
临床资料
其他名称PRO-LAD,
6-propyl- 6-nor- Lysergic acid diethylamide,
(6aR,9R)- N,N- diethyl- 7-propyl- 4,6,6a,7,8,9- hexahydroindolo- [4,3-fg] quinoline- 9- carboxamide
给药途径口服给药
法律规范状态
法律规范
  • NpSG
  • PSA
  • analogue but only if it is intended for human consumption
  • Illegal in France[1]
药物动力学数据
药物代谢Hepatic
排泄途径Renal
识别信息
  • (8β)-N,N-Diethyl-6-propyl-9,10-didehydroergoline-8-carboxamide
CAS号65527-63-1  checkY
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
化学信息
化学式C22H29N3O
摩尔质量351.49 g·mol−1
3D模型(JSmol英语JSmol
  • CCN(CC)C(=O)[C@@H]2C=C1c3cccc4[nH]cc(C[C@H]1N(C2)CCC)c34
  • InChI=1S/C22H29N3O/c1-4-10-25-14-16(22(26)24(5-2)6-3)11-18-17-8-7-9-19-21(17)15(13-23-19)12-20(18)25/h7-9,11,13,16,20,23H,4-6,10,12,14H2,1-3H3/t16-,20-/m1/s1 checkY
  • Key:HZKYLVLOBYNKKM-OXQOHEQNSA-N checkY

参考文献

  1. ^ Arrêté du 20 mai 2021 modifiant l'arrêté du 22 février 1990 fixant la liste des substances classées comme stupéfiants [Order of May 20, 2021 amending the order of February 22, 1990 setting the list of substances classified as narcotics]. www.legifrance.gouv.fr. 20 May 2021 (法语). 
  2. ^ Hoffman AJ, Nichols DE. Synthesis and LSD-like discriminative stimulus properties in a series of N(6)-alkyl norlysergic acid N,N-diethylamide derivatives. Journal of Medicinal Chemistry. September 1985, 28 (9): 1252–1255. PMID 4032428. doi:10.1021/jm00147a022. 

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