T-0156
化合物
T-0156,分子式C31H29N5O7,但通常以盐酸盐的形式存在,是一种第五型磷酸二酯酶(PDE5)抑制剂[1][2]。
T-0156 | |
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IUPAC名 Methyl 2-[(2-methylpyridin-4-yl)methyl]-1-oxo-8-(pyrimidin-2-ylmethoxy)-4-(3,4,5-trimethoxyphenyl)-2,7-naphthyridine-3-carboxylate | |
别名 | T0156; Tocris-1676 |
识别 | |
CAS号 | 324572-92-1 |
PubChem | 5368 9852041(盐酸盐) |
ChemSpider | 5175, 8027754 (盐酸盐) |
SMILES |
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InChI |
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InChIKey | JEMJAABFSYOLAP-UHFFFAOYSA-N |
IUPHAR配体 | 5275 |
性质 | |
化学式 | C31H29N5O7 |
摩尔质量 | 583.59 g·mol−1 |
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。 |
参考资料
- ^ Parlak, A; Yildirim, S; Bagcivan, I; Durmus, N. Role of New Agents Affecting NO/cGMP Pathway on Ovalbumin-Sensitized Guinea Pig Trachea. Experimental Lung Research. October 2012, 38 (8): 420–6. PMID 23030645. S2CID 22720639. doi:10.3109/01902148.2012.719281.
- ^ Santos, AI; Carreira, BP; Nobre, RJ; Carvalho, CM; Araújo, IM. Stimulation of Neural Stem Cell Proliferation by Inhibition of Phosphodiesterase 5. Stem Cells International. 2014, 2014: 878397. PMC 3914480 . PMID 24550991. doi:10.1155/2014/878397.