蛋白質合成GTP酶

蛋白質合成GTP酶(英語:Protein-synthesizing GTPasesEC 3.6.5.3)是指許多參與mRNA翻譯為蛋白質的起始因子(IF)、延伸因子(EF)和釋放因子(RF),其系統名為GTP phosphohydrolase (mRNA-translation-assisting)[1][2][3][4][5],包括翻譯的起始因子IF-2延伸因子EF-Tu

Protein-synthesizing GTPase
蛋白質合成相關GTP酶
識別碼
EC編號 3.6.5.3
資料庫
IntEnz IntEnz瀏覽
BRENDA英語BRENDA BRENDA入口
ExPASy英語ExPASy NiceZyme瀏覽
KEGG KEGG入口
MetaCyc英語MetaCyc 代謝路徑
PRIAM英語PRIAM_enzyme-specific_profiles 概述
PDB RCSB PDB PDBj PDBe PDBsum

參考文獻

  1. ^ Kurzchalia, T.V., Bommer, U.A., Babkina, G.T. and Karpova, G.G. GTP interacts with the γ-subunit of eukaryotic initiation factor EIF-2. FEBS Lett. 1984, 175 (2): 313–316. PMID 6566615. 
  2. ^ Kisselev, L.L. and Frolova, L.Yu. Termination of translation in eukaryotes. Biochem. Cell Biol. 1995, 73 (11-12): 1079–1086. PMID 8722024. 
  3. ^ Rodnina, M.V., Savelsberg, A., Katunin, V.I. and Wintermeyer, W. Hydrolysis of GTP by elongation factor G drives tRNA movement on the ribosome. Nature. 1997, 385 (6611): 37–41. PMID 8985244. doi:10.1038/385037a0. 
  4. ^ Freistroffer, D.V., Pavlov, M.Y., MacDougall, J., Buckingham, R.H. and Ehrenberg, M. Release factor RF3 in E. coli accelerates the dissociation of release factors RF1 and RF2 from the ribosome in a GTP-dependent manner. EMBO J. 1997, 16: 4126–4133. PMID 9233821. doi:10.1093/emboj/16.13.4126. 
  5. ^ Krab, I.M. and Parmeggiani, A. EF-Tu, a GTPase odyssey. Biochim. Biophys. Acta. 1998, 1443 (1-2): 1–22. PMID 9838020. 

外部連結