1-疊氮丙烷

1-疊氮丙烷是一種有機化合物,化學式為C3H7N3。它可由1-溴丙烷疊氮化鈉H2O-THF中回流反應得到。[3]它可用於合成三唑類化合物,如和丙炔反應,得到1-丙基-4-甲基-1H-1,2,3-三唑[4];和乙醯乙酸乙酯反應,得到1-丙基-5-甲基-1H-1,2,3-三唑-4-甲酸乙酯[5]

n-Propyl azide
Skeletal formula of propyl azide
Ball-and-stick model of the propyl azide molecule
IUPAC名
1-Azidopropane
別名 1-疊氮基丙烷
疊氮正丙烷
識別
CAS號 22293-25-0  checkY
PubChem 12405072
ChemSpider 14073926
SMILES
 
  • [N-]=[N+]=NCCC
InChI
 
  • 1/C3H7N3/c1-2-3-5-6-4/h2-3H2,1H3
InChIKey TVPPZASKIXGUJQ-UHFFFAOYAK
性質
化學式 C3H7N3
摩爾質量 85.11 g·mol−1
密度 0.8859 g·cm−3(20 °C)[1]
沸點 79 °C(352 K)[2]
81—82 °C(354—355 K)[3]
危險性
主要危害 有害;易爆
若非註明,所有數據均出自標準狀態(25 ℃,100 kPa)下。

參考文獻

  1. ^ Stolyarov, B. V.; Shavarda, A. L. Synthesis of alkyl azides in a preparative gas-chromatographic column. Zhurnal Organicheskoi Khimii, 1978. 14 (1): 202-203. ISSN: 0514-7492.
  2. ^ Lieber, Eugene; Ramachandra Rao, C. N.; Chao, Tai Siang; Wahl, Werner H. Physical studies on organic azides. Journal of Scientific & Industrial Research, 1957. 16B: 95-97. ISSN: 0022-4456.
  3. ^ 3.0 3.1 M. Swetha, P. Venkata Ramana, S. G. Shirodkar. Simple and Efficient Method for the Synthesis of Azides in Water-THF Solvent System. Organic Preparations and Procedures International. 2011-01, 43 (4): 348–353 [2021-01-12]. ISSN 0030-4948. doi:10.1080/00304948.2011.594002 (英語). 
  4. ^ Fangyong Yan, Michael Lartey, Kuldeep Jariwala, Sage Bowser, Krishnan Damodaran, Erik Albenze, David R. Luebke, Hunaid B. Nulwala, Berend Smit, Maciej Haranczyk. Toward a Materials Genome Approach for Ionic Liquids: Synthesis Guided by Ab Initio Property Maps. The Journal of Physical Chemistry B. 2014-11-26, 118 (47): 13609–13620 [2021-01-12]. ISSN 1520-6106. doi:10.1021/jp506972w (英語). 
  5. ^ Zhen-Jun Wang, Yang Gao, Yan-Ling Hou, Cheng Zhang, Shu-Jing Yu, Qiang Bian, Zheng-Ming Li, Wei-Guang Zhao. Design, synthesis, and fungicidal evaluation of a series of novel 5-methyl-1H-1,2,3-trizole-4-carboxyl amide and ester analogues. European Journal of Medicinal Chemistry. 2014-10, 86: 87–94 [2021-01-12]. doi:10.1016/j.ejmech.2014.08.029. (原始內容存檔於2020-02-12) (英語).