2-甲基-5-乙基吡啶
化合物
2-甲基-5-乙基吡啶是一種有機化合物,化學式為(C2H5)(CH3)C5H3N,是無色液體,可用於製備煙酸。[1]它可由2-甲基-5-乙基哌啶的脫氫反應製得。[2]甲醛和氨的反應也能製得2-甲基-5-乙基吡啶。[3]它和高錳酸鉀在鹼性溶液中氧化,可以得到2,5-吡啶二甲酸等產物;[4]它在冰乙酸中被過氧化氫氧化,得到2-甲基-5-乙基吡啶-N-氧化物。[5]
2-甲基-5-乙基吡啶 | |
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別名 | 5-乙基-2-甲基吡啶 |
識別 | |
CAS號 | 104-90-5 |
PubChem | 7728 |
ChemSpider | 21105900 |
SMILES |
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Beilstein | 109269 |
UN編號 | 2300 |
RTECS | TJ6825000 |
性質 | |
化學式 | C8H11N |
摩爾質量 | 121.18 g·mol−1 |
外觀 | 無色液體 |
密度 | 0.9208 g/cm3 |
熔點 | −70.3 °C(203 K) |
沸點 | 178 °C(451 K) |
溶解性(水) | 1.2 g/100 mL |
危險性 | |
GHS危險性符號 | |
GHS提示詞 | 危險 |
H-術語 | H302, H311, H314, H315, H317, H319, H331, H412 |
P-術語 | P260, P261, P264, P270, P271, P272, P273, P280, P301+312, P301+330+331, P302+352, P303+361+353, P304+340, P305+351+338 |
若非註明,所有數據均出自標準狀態(25 ℃,100 kPa)下。 |
參考文獻
- ^ Shimizu, Shinkichi; Watanabe, Nanao; Kataoka, Toshiaki; Shoji, Takayuki; Abe, Nobuyuki; Morishita, Sinji; Ichimura, Hisao, Pyridine and Pyridine Derivatives, Ullmann's Encyclopedia of Industrial Chemistry, Weinheim: Wiley-VCH, 2005, doi:10.1002/14356007.a22_399
- ^ Jacob Finkelstein, Robert C. Elderfield. STUDIES IN THE PYRIDINE SERIES. I. AN IMPROVED SYNTHESIS OF 2,3-DIMETHYLPYRIDINE AND THE CONVERSION OF THE LATTER INTO AN ANALOG OF THIAMINE. The Journal of Organic Chemistry. 1939-09, 04 (4): 365–375 [2021-04-07]. ISSN 0022-3263. doi:10.1021/jo01216a002 (英語).
- ^ K.V.V. Krishna Mohan, K. Suresh Kumar Reddy, N. Narender, S.J. Kulkarni. Zeolite catalysed synthesis of 5-ethyl-2-methylpyridine under high pressure. Journal of Molecular Catalysis A: Chemical. 2009-02, 298 (1-2): 99–102 [2021-04-07]. doi:10.1016/j.molcata.2008.10.010 (英語).
- ^ Nurullaeva, M. K.; Azizov, U. M.; Azimov, V. A.; Yakhontov, L. N. Synthesis and conversions of (2-methyl-5-pyridyl)glyoxylic acid derivatives. Khimiko-Farmatsevticheskii Zhurnal, 1989. 23 (8): 985-987. ISSN: 0023-1134.
- ^ Veronika F.S. Pape, Dóra Türk, Pál Szabó, Michael Wiese, Eva A. Enyedy, Gergely Szakács. Synthesis and characterization of the anticancer and metal binding properties of novel pyrimidinylhydrazone derivatives. Journal of Inorganic Biochemistry. 2015-03, 144: 18–30 [2021-04-07]. doi:10.1016/j.jinorgbio.2014.12.015. (原始內容存檔於2018-06-23) (英語).