N-苯乙基哌啶

化合物

N-苯乙基哌啶(英語:1-(2-phenylethyl)piperidine,或稱為1-苯乙基哌啶,開發代號:AC927),分子式C13H19N,是一種選擇性的σ-受體受體拮抗劑[1]

N-苯乙基哌啶
識別資訊
  • 1-(2-phenylethyl)piperidine or N-phenethyl-piperidine
CAS號332-14-9  checkY
ChemSpider
UNII
CompTox Dashboard英語CompTox Chemicals Dashboard (EPA)
ECHA InfoCard100.005.785 編輯維基數據鏈接
化學資訊
化學式C13H19N
摩爾質量189.30 g·mol−1

合成

N-苯乙基哌啶可由哌啶苯乙烯在一種有機鎂化合物的催化下反應製得。[2]

參考文獻

  1. ^ Matsumoto RR, Shaikh J, Wilson LL, Vedam S, Coop A. Attenuation of methamphetamine-induced effects through the antagonism of sigma (σ) receptors: Evidence from in vivo and in vitro studies. Eur. Neuropsychopharmacol. 2008, 18 (12): 871–81. PMC 2688716 . PMID 18755577. doi:10.1016/j.euroneuro.2008.07.006. 
  2. ^ Davin, Laia; Hernán-Gómez, Alberto; McLaughlin, Calum; Kennedy, Alan R.; McLellan, Ross; Hevia, Eva. Alkali metal and stoichiometric effects in intermolecular hydroamination catalysed by lithium, sodium and potassium magnesiates. Dalton Transactions (Royal Society of Chemistry (RSC)). 2019, 48 (23): 8122–8130. ISSN 1477-9226. doi:10.1039/c9dt00923j.