21-去氧皮質醇
化合物
21-去氧皮質醇(英語:21-Deoxycortisol,也稱為11β,17α-二羥基孕酮,11β,17α-dihydroxyprogesterone,或11β,17α-二羥基孕-4-烯-3,20-二酮,11β,17α-dihydroxypregn-4-ene-3,20-dione)是一種與皮質醇(11β,17α,21-三羥基孕酮)有關的天然內源性甾體物質,可由類固醇11-β-羥化酶(CYP11B1)代謝17α-羥孕酮生成[1]。
21-去氧皮質醇 | |
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IUPAC名 (8S,9S,10R,11S,13S,14S,17R)-17-acetyl-11,17-dihydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one | |
別名 | 21-Desoxycortisol; 21-Dehydrohydrocortisone; 21-Deoxyhydrocortisone; 11β,17α-Dihydroxyprogesterone; 11β,17α-Dihydroxypregn-4-ene-3,20-dione |
識別 | |
CAS號 | 641-77-0 |
PubChem | 92827 |
ChemSpider | 83796 |
SMILES |
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ChEBI | 28697 |
KEGG | C05497 |
性質 | |
化學式 | C21H30O4 |
摩爾質量 | 346.46 g·mol−1 |
若非註明,所有數據均出自標準狀態(25 ℃,100 kPa)下。 |
參考文獻
- ^ Cristoni S, Cuccato D, Sciannamblo M, Bernardi LR, Biunno I, Gerthoux P, Russo G, Weber G, Mora S. Analysis of 21-deoxycortisol, a marker of congenital adrenal hyperplasia, in blood by atmospheric pressure chemical ionization and electrospray ionization using multiple reaction monitoring. Rapid Commun. Mass Spectrom. 2004, 18 (1): 77–82. Bibcode:2004RCMS...18...77C. PMID 14689562. doi:10.1002/rcm.1284.
外部連結
這是一篇關於類固醇的小作品。您可以透過編輯或修訂擴充其內容。 |