帽柱木碱
化合物
帽柱木碱(英语:Mitragynine)是一种有机化合物,分子式C23H30N2O4,属于吲哚生物碱,存在于卡痛树(Mitragyna speciosa)等植物中,用作精神药物[4]。
临床资料 | |
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给药途径 | 口服给药 |
药物类别 | 鸦片 |
ATC码 |
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法律规范状态 | |
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药物动力学数据 | |
生物利用度 | 21% |
代谢产物 | 7-羟基帽柱碱 |
生物半衰期 | 7–39 hours |
识别信息 | |
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CAS号 | 4098-40-2 |
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ChEMBL | |
CompTox Dashboard (EPA) | |
化学信息 | |
化学式 | C23H30N2O4 |
摩尔质量 | 398.50 g·mol−1 |
3D模型(JSmol) | |
熔点 | 102–106 °C[3] |
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参考文献
- ^ 指定薬物一覧 [List of designated drugs] (PDF). 障害福祉のお仕事の世界 (The world of disability welfare work). [5 December 2023] (Japanese).
- ^ Anvisa. RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial [Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control]. Diário Oficial da União. 2023-03-31 (2023-04-04) [2023-08-15]. (原始内容存档于2023-08-03) (巴西葡萄牙语).
- ^ Kratom profile (chemistry, effects, other names, origin, mode of use, other names, medical use, control status). European Monitoring Centre for Drugs and Drug Addiction (EMCDDA).
- ^ Hassan Z, Muzaimi M, Navaratnam V, Yusoff NH, Suhaimi FW, Vadivelu R, Vicknasingam BK, Amato D, von Hörsten S, Ismail NI, Jayabalan N, Hazim AI, Mansor SM, Müller CP. From Kratom to mitragynine and its derivatives: physiological and behavioural effects related to use, abuse, and addiction. Neuroscience and Biobehavioral Reviews. February 2013, 37 (2): 138–151. PMID 23206666. S2CID 8463133. doi:10.1016/j.neubiorev.2012.11.012.