帽柱木鹼
化合物
帽柱木鹼(英語:Mitragynine)是一種有機化合物,分子式C23H30N2O4,屬於吲哚生物鹼,存在於卡痛樹(Mitragyna speciosa)等植物中,用作精神藥物[4]。
臨床資料 | |
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給藥途徑 | 口服給藥 |
藥物類別 | 鴉片 |
ATC碼 |
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法律規範狀態 | |
法律規範 | |
藥物動力學數據 | |
生物利用度 | 21% |
代謝產物 | 7-羥基帽柱鹼 |
生物半衰期 | 7–39 hours |
識別資訊 | |
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CAS號 | 4098-40-2 |
PubChem CID | |
ChemSpider | |
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KEGG | |
ChEBI | |
ChEMBL | |
CompTox Dashboard (EPA) | |
化學資訊 | |
化學式 | C23H30N2O4 |
摩爾質量 | 398.50 g·mol−1 |
3D模型(JSmol) | |
熔點 | 102–106 °C[3] |
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參考文獻
- ^ 指定薬物一覧 [List of designated drugs] (PDF). 障害福祉のお仕事の世界 (The world of disability welfare work). [5 December 2023] (Japanese).
- ^ Anvisa. RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial [Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control]. Diário Oficial da União. 2023-03-31 (2023-04-04) [2023-08-15]. (原始內容存檔於2023-08-03) (巴西葡萄牙語).
- ^ Kratom profile (chemistry, effects, other names, origin, mode of use, other names, medical use, control status). European Monitoring Centre for Drugs and Drug Addiction (EMCDDA).
- ^ Hassan Z, Muzaimi M, Navaratnam V, Yusoff NH, Suhaimi FW, Vadivelu R, Vicknasingam BK, Amato D, von Hörsten S, Ismail NI, Jayabalan N, Hazim AI, Mansor SM, Müller CP. From Kratom to mitragynine and its derivatives: physiological and behavioural effects related to use, abuse, and addiction. Neuroscience and Biobehavioral Reviews. February 2013, 37 (2): 138–151. PMID 23206666. S2CID 8463133. doi:10.1016/j.neubiorev.2012.11.012.