绒毛羊膜炎

绒毛羊膜炎,又名为内羊膜炎(intra-amniotic inflammationIAI),是胎膜羊水胎盘炎症,常由感染引起[2] [3]。症状通常包括发烧、腹痛、母亲或胎儿心率过快、或异常的阴道分泌物[4]。新生儿并发症可能包括肺炎脑膜炎败血症早产脑性麻痹[3] [5]。母亲的并发症可能包括产后出血子宫内膜炎败血症急性呼吸窘迫症候群[3]

绒毛羊膜炎
显微图显示急性绒毛膜羊膜炎,绒毛膜中有中性粒细胞。还有纤维蛋白血栓,代表严重的胎儿发炎反应。[1]苏木精-伊红染色.
分类和外部资源
医学专科妇产科学
ICD-10O41.1、​P02.7
DiseasesDB31882
eMedicine973237
[编辑此条目的维基数据]

危险因子包括分娩时间较长胎膜早破、既往妊娠次数少、产道内有B 组链球菌移生和胎膜破裂后频繁地进行阴道检查[3] [6]。可能的机转通常是细菌阴道进入子宫[4] [7]。引起发炎,并造成子宫收缩,并可能早产[7]。若出现单次体温超过39.0 °C(102.2 °F)或持续在38.0 °C(100.4 °F)和39.0 °C(102.2 °F)间,就需高度怀疑患者是否有这个诊断 [3]

使用抗生素治疗,常用氨苄西林庆大霉素[3] [6]。可用乙酰氨基酚(对乙酰氨基酚)降低体温[6]。有早产风险的患者,也可能使用皮质类固醇[5]。虽然通常应该及时进行生产,但通常不需剖腹产[3] [6]。羊膜囊早期破裂的患者,通常会预防性使用抗生素[5]

绒毛膜羊膜炎的发生率,在足月产约为 4%,在早产则约在 40% 至 70%,而怀孕不足 24 周的生产中则约为 94%[2] [8]。分娩时的发烧,有 10% 至 40% 是由此引起[9]


参见

参考文献

  1. ^ Kim CJ, Romero R, Chaemsaithong P, Chaiyasit N, Yoon BH, Kim YM. Acute chorioamnionitis and funisitis: definition, pathologic features, and clinical significance. American Journal of Obstetrics and Gynecology. October 2015, 213 (4 Suppl): S29–S52. PMC 4774647 . PMID 26428501. doi:10.1016/j.ajog.2015.08.040. 
  2. ^ 2.0 2.1 Kim, Chong Jai; Romero, Roberto; Chaemsaithong, Piya; Chaiyasit, Noppadol; Yoon, Bo Hyun; Kim, Yeon Mee. Acute chorioamnionitis and funisitis: definition, pathologic features, and clinical significance. American Journal of Obstetrics and Gynecology. 2015, 213 (4): S29–S52. ISSN 0002-9378. PMC 4774647 . PMID 26428501. doi:10.1016/j.ajog.2015.08.040. 
  3. ^ 3.0 3.1 3.2 3.3 3.4 3.5 3.6 Committee Opinion No. 712: Intrapartum Management of Intraamniotic Infection.. Obstetrics and gynecology. August 2017, 130 (2): e95-e101 [17 January 2024]. PMID 28742677. doi:10.1097/AOG.0000000000002236. (原始内容存档于26 September 2023). 
  4. ^ 4.0 4.1 Fowler, JR; Simon, LV. Chorioamnionitis.. StatPearls. January 2023 [17 January 2024]. PMID 30335284. (原始内容存档于31 January 2021). 
  5. ^ 5.0 5.1 5.2 Ericson JE, Laughon MM. Chorioamnionitis: implications for the neonate. Clinics in Perinatology. March 2015, 42 (1): 155–65, ix. PMC 4331454 . PMID 25678002. doi:10.1016/j.clp.2014.10.011. 
  6. ^ 6.0 6.1 6.2 6.3 Intraamniotic Infection - Gynecology and Obstetrics. Merck Manuals Professional Edition. [17 January 2024]. (原始内容存档于2 October 2023) (加拿大英语). 
  7. ^ 7.0 7.1 Galinsky R, Polglase GR, Hooper SB, Black MJ, Moss TJ. The consequences of chorioamnionitis: preterm birth and effects on development. Journal of Pregnancy. 2013, 2013: 412831. PMC 3606792 . PMID 23533760. doi:10.1155/2013/412831 . 
  8. ^ Radswiki, The. Chorioamnionitis | Radiology Reference Article | Radiopaedia.org. Radiopaedia. [18 January 2024]. (原始内容存档于16 December 2023). 
  9. ^ Gravett, Michael G. Intra-amniotic and Postpartum Infections. The Global Library of Women's Medicine. 2009 [18 January 2024]. doi:10.3843/GLOWM.10176. (原始内容存档于24 September 2023). 
  • Verani JR, McGee L, Schrag SJ. Prevention of perinatal group B streptococcal disease--revised guidelines from CDC, 2010. MMWR. Recommendations and Reports. November 2010, 59 (RR-10): 1–36. PMID 21088663. 

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