咽喉反流

咽喉反流(Laryngopharyngeal reflux,缩写 LPR)[1][2],又称为喉咽回流、咽喉逆流症、咽喉胃酸逆流、胃食管外反流疾病(extraesophageal reflux disease,缩写 EERD)[3],是指胃酸逆行流到上呼吸消化道的现象,如此现象会导致多种症状,如咳嗽声音嘶哑喘息,等等症状。咽喉反流为哮喘的相关的合并症[4]

Sagittal illustration of the anterior portion of the human head and neck. In LPR, the pharynx (1) and larynx (3) are exposed to gastric contents that flow upward through the esophagus (4).

虽然胃灼热是人们胃食管反流病(GERD)的主要症状,然而胃灼热存在的患者之 LPR 少于50%。用来描述这种情况的其他术语包括“非典型回流”、[5]沉默回流,[6]以及“上食道回流”。[7]

注释

  1. ^ Laryngopharyngeal Reflux页面存档备份,存于互联网档案馆), New York-Presbyterian Hospital, Weill Cornell Medical Center
  2. ^ Laryngopharyngeal Reflux (LPR)页面存档备份,存于互联网档案馆), About.com
  3. ^ Kahrilas PJ. Maximizing outcome of extraesophageal reflux disease. Am J Manag Care. October 2000, 6 (16 Suppl): S876–82. PMID 11184658. 
  4. ^ Cazzola M, Segreti A, Calzetta L, Rogliani P. Comorbidities of asthma: current knowledge and future research needs (PDF). Current Opinion in Pulmonary Medicine. 2013, 19 (1): 36–41 [2016-08-21]. PMID 23114561. doi:10.1097/MCP.0b013e32835b113a. (原始内容存档 (PDF)于2016-08-23). 
  5. ^ MARCI-Kids Midwest Acid Reflux Children's Institute. [29 April 2010]. (原始内容存档于2017-06-28). 
  6. ^ Koufman JA. Laryngopharyngeal reflux is different from classic gastroesophageal reflux disease. Ear, Nose, & Throat Journal. 2002, 81 (9 Suppl 2): 7–9. PMID 12353431. 
  7. ^ Zerbib F, Stoll D. Management of laryngopharyngeal reflux: an unmet medical need.. Neurogastroenterol Motil. 2010, 22 (2): 109–12. PMID 20067549. doi:10.1111/j.1365-2982.2009.01437.x. 

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